Chemokine (C-C Motif) Receptor 2 (CCR2) (C-Term) Peptid
Kurzübersicht für Chemokine (C-C Motif) Receptor 2 (CCR2) (C-Term) Peptid (ABIN974623)
Target
Spezies
Quelle
Applikation
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Protein Region
- C-Term
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Sequenz
- FTIMIVYFLF WTPYNIVILL NTFQEFFGLS NCESTSQLDQ ATQVTETLGM
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-CCR2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CCR2 (Chemokine (C-C Motif) Receptor 2 (CCR2))
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Hintergrund
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This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The receptors encoded by this gene mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase.
Alias Symbols: CKR2, CCR-2, CCR2A, CCR2B, CD192, CKR2A, CKR2B, CMKBR2, MCP-1-R, CC-CKR-2
Protein Size: 374 -
Molekulargewicht
- 42 kDa
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Gen-ID
- 1231
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NCBI Accession
- NM_000647, NP_000638
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UniProt
- P41597
Target
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