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Chemokine (C-C Motif) Receptor 2 (CCR2) (C-Term) Peptid

CCR2 Reaktivität: Human Wirt: Synthetic BP, WB

Produktnummer ABIN974623

Datenblatt (PDF)

Kurzübersicht für Chemokine (C-C Motif) Receptor 2 (CCR2) (C-Term) Peptid (ABIN974623)

Target

CCR2 (Chemokine (C-C Motif) Receptor 2 (CCR2))

Spezies

Human

Quelle

Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB)

Protein Region

C-Term

Sequenz

FTIMIVYFLF WTPYNIVILL NTFQEFFGLS NCESTSQLDQ ATQVTETLGM

Produktmerkmale

This is a synthetic peptide designed for use in combination with anti-CCR2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

Aufreinigung

Purified
Chemokine (C-C Motif) Receptor 2 (CCR2) peptide
CCR2 Reaktivität: Säugetier Wirt: Synthetic BP, WB, IHC

Chemokine (C-C Motif) Receptor 2 (CCR2) (Middle Region) peptide
CCR2 Reaktivität: Human Wirt: Synthetic BP, WB

Chemokine (C-C Motif) Receptor 2 (CCR2) (N-Term) peptide
CCR2 Reaktivität: Human Wirt: Synthetic BP, WB

Chemokine (C-C Motif) Receptor 2 (CCR2) peptide
CCR2 Reaktivität: Human Wirt: Synthetic BP, WB, ICo, IDe

Applikationshinweise

Each Investigator should determine their own optimal working dilution for specific applications.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Lyophilized

Rekonstitution

Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

Konzentration

1 mg/mL

Buffer

Final peptide concentration is 1 mg/mL in PBS.

Handhabung

Avoid repeated freeze-thaw cycles.

Lagerung

-20 °C

Informationen zur Lagerung

For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Target

CCR2 (Chemokine (C-C Motif) Receptor 2 (CCR2))

Hintergrund

This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The receptors encoded by this gene mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase.

Alias Symbols: CKR2, CCR-2, CCR2A, CCR2B, CD192, CKR2A, CKR2B, CMKBR2, MCP-1-R, CC-CKR-2

Protein Size: 374

Molekulargewicht

42 kDa

Gen-ID

1231

NCBI Accession

NM_000647, NP_000638

UniProt

P41597

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