Pseudouridylate Synthase 10 (PUS10) (Middle Region) Peptid
PUS10
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN974538
Kurzübersicht für Pseudouridylate Synthase 10 (PUS10) (Middle Region) Peptid (ABIN974538)
Target
PUS10
(Pseudouridylate Synthase 10 (PUS10))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequenz
- AVFVAGRYNK YSRNLPQTPW IIDGERKLES SVEELISDHL LAVFKAESFN
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-CCDC139 Antibody(ARP52750_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PUS10 (Pseudouridylate Synthase 10 (PUS10))
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Hintergrund
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Pseudouridination, the isomerization of uridine to pseudouridine, is the most common posttranscriptional nucleotide modification found in RNA and is essential for biologic functions such as spliceosome biogenesis. Pseudouridylate synthases, such as PUS10, catalyze pseudouridination of structural RNAs, including transfer, ribosomal, and splicing RNAs. These enzymes also act as RNA chaperones, facilitating the correct folding and assembly of tRNAs (McCleverty et al., 2007 [PubMed 17900615]).
Alias Symbols: FLJ32312, MGC126729, MGC126755, DOBI, CCDC139
Protein Size: 529 -
Molekulargewicht
- 60 kDa
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Gen-ID
- 150962
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NCBI Accession
- NM_144709, NP_653310
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UniProt
- Q3MIT2
Target
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