Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10) (Middle Region) Peptid
CASP10
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN974472
150,78 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μg
Lieferung nach:
Deutschland
Lieferung in 15 bis 22 Werktagen
Kurzübersicht für Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10) (Middle Region) Peptid (ABIN974472)
Target
Caspase 10 (CASP10)
(Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequenz
- HNNVTKVEME MVLQKQKCNP AHADGDCFVF CILTHGRFGA VYSSDEALIP
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-CASP10 Antibody,. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Caspase 10 (CASP10) (Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10))
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Hintergrund
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This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in this gene are associated with apoptosis defects seen in type II autoimmune lymphoproliferative syndrome. Three alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Alias Symbols: ALPS2, FLICE2, MCH4
Protein Interaction Partner: RB1,BFAR,BID,CASP10,CASP14,CASP2,CASP3,CASP4,CASP6,CASP7,CASP8,CASP9,CCAR1,CFLAR,DEDD,DEDD2,DSP,FADD,POLR2A,RB1,RYBP,TNFRSF1A,TRAF1,AIF1,ARHGDIA,BID,CASP1,CASP10,CASP14,CASP2,CASP3,CASP4,CASP6,CASP7,CASP8,CASP9,CFLAR,DEDD,DEDD2,EZR,FADD,FAS,FASLG,MAP3K14,
Protein Size: 479 -
Molekulargewicht
- 12 kDa
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Gen-ID
- 843
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NCBI Accession
- NM_001230, NP_001221
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UniProt
- Q92851
Target
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