Caspase Recruitment Domain Family, Member 17 (CARD17) (Middle Region) Peptid
CARD17
Reaktivität: Human
Wirt: Synthetic
BP, WB
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- Target Alle CARD17 Produkte
- CARD17 (Caspase Recruitment Domain Family, Member 17 (CARD17))
- Protein Region
- Middle Region
- Spezies
- Human
-
Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Sequenz
- MDKARALLDS VIRKGAPACQ ICITYICEED SHLAGTLGLS AGPTSGNHLT
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-CARD17 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Aufreinigung
- Purified
-
-
- Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Konzentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
- Target
- CARD17 (Caspase Recruitment Domain Family, Member 17 (CARD17))
- Hintergrund
-
As a regulator of procaspase-1/CASP1 activation, CARD17 is implicated in the regulation of the proteolytic maturation of pro-IL-1beta/IL1B and its release during inflammation. CARD17 inhibits the release of IL1B in response to LPS in monocytes. However, unlike CASP1, CARD17 do not induce NF-kappa-B activation.
Alias Symbols: INCA
Protein Interaction Partner: CARD16,CARD17,CARD18,CASP1
Protein Size: 110 - Molekulargewicht
- 12 kDa
- Gen-ID
- 440068
- NCBI Accession
- NM_001007232, NP_001007233
- UniProt
- Q5XLA6
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