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Bromodomain Containing 4 (BRD4) Peptid

BRD4 Reaktivität: Human Wirt: Synthetic BP, WB, IF, ChIP
Produktnummer ABIN973879
  • Target Alle BRD4 Produkte
    BRD4 (Bromodomain Containing 4 (BRD4))
    Spezies
    Human
    Quelle
    • 2
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB), Immunofluorescence (IF), Chromatin Immunoprecipitation (ChIP)
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-BRD4 antibody (Catalog #: ARP39076_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    BRD4 (Bromodomain Containing 4 (BRD4))
    Synonyme
    brd4-b Peptide, BRD4 Peptide, fb18g03 Peptide, wu:fb18g03 Peptide, CAP Peptide, HUNK1 Peptide, HUNKI Peptide, MCAP Peptide, Brd5 Peptide, WI-11513 Peptide, bromodomain containing 4 L homeolog Peptide, bromodomain containing 4 Peptide, bromodomain-containing protein 4 Peptide, brd4.L Peptide, BRD4 Peptide, brd4 Peptide, LOC100409351 Peptide, Brd4 Peptide
    Hintergrund
    BRD4 is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting.The protein encoded by this gene is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. This gene has been implicated as the chromosome 19 target of translocation t(15,19)(q13,p13.1), which defines an upper respiratory tract carcinoma in young people. Two alternatively spliced transcript variants have been described.

    Alias Symbols: CAP, HUNKI, MCAP, HUNK1

    Protein Interaction Partner: E2,C7orf25,CHFR,CLDN1,PRPF40A,RFC1,RFC4,CCNT1,CCNT2,CDK9,HEXIM1,HIST2H3C,HIST2H4A,HIST4H4,MED12,MED14,MED17,MED24,RFC1,RFC2,RFC3,RFC4,RFC5,SIPA1

    Protein Size: 722
    Molekulargewicht
    80 kDa
    Gen-ID
    23476
    NCBI Accession
    NM_014299, NP_055114
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