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Bol, Boule-Like (BOLL) Peptid

BOLL Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN973860

Kurzübersicht für Bol, Boule-Like (BOLL) Peptid (ABIN973860)

Target

BOLL (Bol, Boule-Like (BOLL))

Spezies

Human

Quelle

  • 3
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB)
  • Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti-BOLL antibody (Catalog #: ARP41065_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Aufreinigung

    Purified
  • Applikationshinweise

    Each Investigator should determine their own optimal working dilution for specific applications.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Konzentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    BOLL (Bol, Boule-Like (BOLL))

    Hintergrund

    This gene belongs to the DAZ gene family required for germ cell development. BOLL is an RNA-binding protein which is more similar to Drosophila Boule than to human proteins encoded by genes DAZ (deleted in azoospermia) or DAZL (deleted in azoospermia-like). Loss of this gene function results in the absence of sperm in semen (azoospermia). Histological studies demonstrated that the primary defect is at the meiotic G2/M transition. This gene belongs to the DAZ gene family required for germ cell development. It encodes an RNA-binding protein which is more similar to Drosophila Boule than to human proteins encoded by genes DAZ (deleted in azoospermia) or DAZL (deleted in azoospermia-like). Loss of this gene function results in the absence of sperm in semen (azoospermia). Histological studies demonstrated that the primary defect is at the meiotic G2/M transition. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

    Alias Symbols: BOULE

    Protein Interaction Partner: DAZ1,DAZ4

    Protein Size: 283

    Molekulargewicht

    31 kDa

    Gen-ID

    66037

    NCBI Accession

    NM_033030, NP_149019

    UniProt

    Q8N9W6
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