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BH3 Interacting Domain Death Agonist (BID) (C-Term) Peptid

BID Reaktivität: Human Wirt: Synthetic BP, ICC, WB
Produktnummer ABIN973819

Kurzübersicht für BH3 Interacting Domain Death Agonist (BID) (C-Term) Peptid (ABIN973819)

Target

BID (BH3 Interacting Domain Death Agonist (BID))

Spezies

Human

Quelle

  • 5
Synthetic

Applikation

Blocking Peptide (BP), Immunocytochemistry (ICC), Western Blotting (WB)
  • Protein Region

    C-Term

    Sequenz

    LRNTSRSEED RNRDLATALE QLLQAYPRDM EKEKTMLVLA LLLAKKVASH

    Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti-BID Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Aufreinigung

    Purified
  • Applikationshinweise

    Each Investigator should determine their own optimal working dilution for specific applications.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Konzentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    BID (BH3 Interacting Domain Death Agonist (BID))

    Hintergrund

    This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8), CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined.

    Alias Symbols: FP497, MGC15319, MGC42355

    Protein Interaction Partner: BAX,BCL2,BCL2,BCL2A1,BCL2L1,BCL2L1,BCL2L1,BCL2L2,BNC1,PACS2,BCL2L1,BAK1,BAX,BCL2,BCL2A1,BCL2L1,BCL2L2,BID,CAPN1,CASP1,CASP10,CASP2,CASP3,CASP8,CSNK1A1,CSNK1E,CSNK2A1,CSNK2A2,CSNK2B,GZMB,MCL1,YWHAB,ARHGDIA,BCL2,BCL2A1,BCL2L1,BCL2L1,BCL2L2,BID,CAPN2,CASP10,

    Protein Size: 241

    Molekulargewicht

    27 kDa

    Gen-ID

    637

    NCBI Accession

    NM_197966, NP_932070

    UniProt

    B3KT21
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