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Bardet-Biedl Syndrome 2 (BBS2) (Middle Region) Peptid

BBS2 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN973750

Kurzübersicht für Bardet-Biedl Syndrome 2 (BBS2) (Middle Region) Peptid (ABIN973750)

Target

BBS2 (Bardet-Biedl Syndrome 2 (BBS2))

Spezies

Human

Quelle

  • 3
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    Middle Region

    Sequenz

    RGYLPGTAEM RGNLMDTSAE QDLIRELSQK KQNLLLELRN YEENAKAELA

    Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti-BBS2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Aufreinigung

    Purified
  • Applikationshinweise

    Each Investigator should determine their own optimal working dilution for specific applications.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Konzentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    BBS2 (Bardet-Biedl Syndrome 2 (BBS2))

    Hintergrund

    This gene is a member of the Bardet-Biedl syndrome (BBS) gene family. Bardet-Biedl syndrome is an autosomal recessive disorder characterized by severe pigmentary retinopathy, obesity, polydactyly, renal malformation and mental retardation. The proteins encoded by BBS gene family members are structurally diverse and the similar phenotypes exhibited by mutations in BBS gene family members is likely due to their shared roles in cilia formation and function. Many BBS proteins localize to the basal bodies, ciliary axonemes, and pericentriolar regions of cells. BBS proteins may also be involved in intracellular trafficking via microtubule-related transport. The protein encoded by this gene forms a multiprotein BBSome complex with six other BBS proteins.

    Alias Symbols: BBS, MGC20703

    Protein Interaction Partner: PSME3,PSME3

    Protein Size: 721

    Molekulargewicht

    80 kDa

    Gen-ID

    583

    NCBI Accession

    NM_031885, NP_114091

    UniProt

    Q9BXC9
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