BCL2-Associated Athanogene 2 (BAG2) Peptid
BAG2
Reaktivität: Human
Wirt: Synthetic
BP, IHC, WB
Produktnummer ABIN973712
Kurzübersicht für BCL2-Associated Athanogene 2 (BAG2) Peptid (ABIN973712)
Target
BAG2
(BCL2-Associated Athanogene 2 (BAG2))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-BAG2 antibody (Catalog #: ARP42177_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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BCL2-Associated Athanogene 2 (BAG2) peptide
BAG2 Reaktivität: Human, Rind (Kuh), Schwein Wirt: Synthetic BP, Imm
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- BAG2 (BCL2-Associated Athanogene 2 (BAG2))
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Hintergrund
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BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.
Alias Symbols: RP3-496N17.2, BAG-2, KIAA0576, MGC149462, dJ417I1.2
Protein Interaction Partner: HSPA1A,HSPA8,MAPKAPK2,HSPA8,MLF2,PSMC4
Protein Size: 211 -
Molekulargewicht
- 23 kDa
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Gen-ID
- 9532
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NCBI Accession
- NM_004282, NP_004273
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UniProt
- O95816
Target
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