This is a synthetic peptide designed for use in combination with anti-BAG1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Each Investigator should determine their own optimal working dilution for specific applications.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Konzentration
1 mg/mL
Buffer
Final peptide concentration is 1 mg/mL in PBS.
Handhabung
Avoid repeated freeze-thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Target
BAG1
(BCL2-Associated Athanogene (BAG1))
Hintergrund
The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. Multiple protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) initiation codon, and three alternative downstream AUG initiation codons. A related pseudogene has been defined on chromosome X.
Alias Symbols: HAP, RAP46
Protein Interaction Partner: HSPA4,AR,BCL2,BCL2L1,ESR1,HBEGF,HSPA1A,HSPA1B,HSPA8,MET,NR3C1,PDGFRB,PPP1R15A,PSMD1,RAF1,RARA,RB1,SIAH1,STUB1,VDR,AR,BCL2,ESR1,HBEGF,HSPA1A,HSPA4,HSPA8,MAPT,NR3C1,PPP1R15A,RAF1,RARA,RB1,SIAH1,STUB1,TP53,UBC,VDR