BCL2-Associated Athanogene (BAG1) (N-Term) Peptid
BAG1
Reaktivität: Human
Wirt: Synthetic
BP, WB
Kurzübersicht für BCL2-Associated Athanogene (BAG1) (N-Term) Peptid (ABIN973710)
Target
BAG1
(BCL2-Associated Athanogene (BAG1))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequenz
- QGEEMNRSQE VTRDEESTRS EEVTREEMAA AGLTVTVTHS NEKHDLHVTS
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-BAG1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- BAG1 (BCL2-Associated Athanogene (BAG1))
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Hintergrund
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The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. Multiple protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) initiation codon, and three alternative downstream AUG initiation codons. A related pseudogene has been defined on chromosome X.
Alias Symbols: HAP, RAP46
Protein Interaction Partner: HSPA4,AR,BCL2,BCL2L1,ESR1,HBEGF,HSPA1A,HSPA1B,HSPA8,MET,NR3C1,PDGFRB,PPP1R15A,PSMD1,RAF1,RARA,RB1,SIAH1,STUB1,VDR,AR,BCL2,ESR1,HBEGF,HSPA1A,HSPA4,HSPA8,MAPT,NR3C1,PPP1R15A,RAF1,RARA,RB1,SIAH1,STUB1,TP53,UBC,VDR
Protein Size: 345 -
Molekulargewicht
- 38 kDa
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Gen-ID
- 573
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NCBI Accession
- NM_004323, NP_004314
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UniProt
- Q99933
Target
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