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Aurora Kinase C (AURKC) (Middle Region) Peptid

AURKC Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN973657
  • Target Alle Aurora Kinase C (AURKC) Produkte
    Aurora Kinase C (AURKC)
    Protein Region
    Middle Region
    Spezies
    Human
    Quelle
    • 3
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-AURKC antibody (Catalog #: ARP53575_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    Aurora Kinase C (AURKC)
    Hintergrund
    AURKC may play a part in organizing microtubules in relation to the function of the centrosome/spindle pole during mitosis.This gene encodes a member of the Aurora subfamily of serine/threonine protein kinases. The encoded protein is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere proteins and may play a role in organizing microtubules in relation to centrosome/spindle function during mitosis. This gene is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Alternative splicing results in multiple transcript variants.

    Alias Symbols: AIE2, AIK3, AurC, STK13, aurora-C, ARK3, SPGF5

    Protein Interaction Partner: INCENP,TACC2

    Protein Size: 309
    Molekulargewicht
    34 kDa
    Gen-ID
    6795
    NCBI Accession
    NM_001015878, NP_001015878
    UniProt
    Q9UQB9
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