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Aurora Kinase C (AURKC) (Middle Region) Peptid

AURKC Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN973657

Kurzübersicht für Aurora Kinase C (AURKC) (Middle Region) Peptid (ABIN973657)

Target

Aurora Kinase C (AURKC)

Spezies

Human

Quelle

  • 3
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    Middle Region

    Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti-AURKC antibody (Catalog #: ARP53575_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Aufreinigung

    Purified
  • Applikationshinweise

    Each Investigator should determine their own optimal working dilution for specific applications.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Konzentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    Aurora Kinase C (AURKC)

    Hintergrund

    AURKC may play a part in organizing microtubules in relation to the function of the centrosome/spindle pole during mitosis.This gene encodes a member of the Aurora subfamily of serine/threonine protein kinases. The encoded protein is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere proteins and may play a role in organizing microtubules in relation to centrosome/spindle function during mitosis. This gene is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Alternative splicing results in multiple transcript variants.

    Alias Symbols: AIE2, AIK3, AurC, STK13, aurora-C, ARK3, SPGF5

    Protein Interaction Partner: INCENP,TACC2

    Protein Size: 309

    Molekulargewicht

    34 kDa

    Gen-ID

    6795

    NCBI Accession

    NM_001015878, NP_001015878

    UniProt

    Q9UQB9
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