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Aurora Kinase A (AURKA) Peptid

AURKA Reaktivität: Human Wirt: Synthetic BP, WB, IHC
Produktnummer ABIN973656

Kurzübersicht für Aurora Kinase A (AURKA) Peptid (ABIN973656)

Target

Aurora A (AURKA) (Aurora Kinase A (AURKA))

Spezies

Human

Quelle

  • 5
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
  • Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti-AURKA antibody (Catalog #: ARP30876_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Aufreinigung

    Purified
  • Applikationshinweise

    Each Investigator should determine their own optimal working dilution for specific applications.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Konzentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    Aurora A (AURKA) (Aurora Kinase A (AURKA))

    Hintergrund

    AURKA is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. It is found at the centrosome in interphase cells and at the spindle poles in mitosis. This protein may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene.The protein encoded by this gene is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. The encoded protein is found at the centrosome in interphase cells and at the spindle poles in mitosis. This gene may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene.

    Alias Symbols: AIK, ARK1, AURA, AURORA2, BTAK, MGC34538, STK15, STK6, STK7, PPP1R47

    Protein Interaction Partner: CHFR,RASA1,TP53,AURKA,AURKAIP1,BRCA1,C13orf34,CDC20,CDC25B,CHFR,CKAP5,GSK3B,MBD3,NDC80,NIN,NME1,NUF2,PML,PPP1CA,PPP1CC,PRKACA,TACC1,TACC3,TP53,TPX2,UBE2N,BRCA1,CDC20,CDKN2A,CHFR,KIF2C,MBD3,NFKBIA,NIN,NME1,PML,RAB10,SOD2,TACC1,TP53,TPX2,UBE2L3,UBE2N

    Protein Size: 403

    Molekulargewicht

    46 kDa

    Gen-ID

    6790

    NCBI Accession

    NM_003600, NP_003591

    UniProt

    O14965
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