ATG5 Autophagy Related 5 (ATG5) (Middle Region) Peptid
ATG5
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN973583
Kurzübersicht für ATG5 Autophagy Related 5 (ATG5) (Middle Region) Peptid (ABIN973583)
Target
ATG5
(ATG5 Autophagy Related 5 (ATG5))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequenz
- RFDQFWAINR KLMEYPAEEN GFRYIPFRIY QTTTERPFIQ KLFRPVAADG
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-ATG5 Antibody(ARP59071_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- ATG5 (ATG5 Autophagy Related 5 (ATG5))
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Hintergrund
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ATG5 is required for autophagy. It conjugates to ATG12 and associates with isolation membrane to form cup-shaped isolation membrane and autophagosome. The conjugate detaches from the membrane immediately before or after autophagosome formation is completed. ATG5 may play an important role in the apoptotic process, possibly within the modified cytoskeleton. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity.
Alias Symbols: APG5, APG5-LIKE, APG5L, ASP, hAPG5
Protein Interaction Partner: ATG10,ATG12,ATG16L1,ATG5,ATG12,ATG16L1,ATG3,IMPDH2,MAP1LC3B,MAP1LC3C,TECPR1,TKT
Protein Size: 275 -
Molekulargewicht
- 32 kDa
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Gen-ID
- 9474
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NCBI Accession
- NM_004849, NP_004840
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UniProt
- Q9H1Y0
Target
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