Activating Transcription Factor 5 (ATF5) (Middle Region) Peptid
ATF5
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN973556
Kurzübersicht für Activating Transcription Factor 5 (ATF5) (Middle Region) Peptid (ABIN973556)
Target
ATF5
(Activating Transcription Factor 5 (ATF5))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-ATF5 antibody (Catalog #: ARP57977_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- ATF5 (Activating Transcription Factor 5 (ATF5))
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Hintergrund
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ATF5 belongs to the bZIP family. It is transcriptional activator which binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters and blocks the differentiation of neuroprogenitor cells into neurons. Its transcriptional activity is enhanced by CCND3 and slightly inhibited by CDK4. Loss of ATF5 is associated with hepatocellular carcinoma.
Alias Symbols: ATFX, FLJ34666, HMFN0395
Protein Interaction Partner: DISC1,CCND3,CDC34,CEBPG,DISC1,GABBR1,GABBR2,CD34,CDC34,DISC1,GABBR1,TRIB3,UBC
Protein Size: 282 -
Molekulargewicht
- 31 kDa
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Gen-ID
- 22809
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NCBI Accession
- NM_012068, NP_036200
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UniProt
- B3KND3
Target
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