Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT) (C-Term) Peptid
ARNT
Reaktivität: Ratte
Wirt: Synthetic
BP, WB
Produktnummer ABIN973441
Kurzübersicht für Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT) (C-Term) Peptid (ABIN973441)
Target
ARNT
(Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT))
Spezies
Ratte
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequenz
- SNEQHVQPTS AQPSSQPEVF QEMLSMLGDQ SNTYNNEEFP DLTMFPPFSE
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-Arnt Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- ARNT (Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT))
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Hintergrund
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Arnt is required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens. The heterodimer with HIF1A or EPAS1/HIF2A functions as a transcriptional regulator of the adaptive response to hypoxia.
Alias Symbols: Arnt1, Arnt
Protein Size: 800 -
Molekulargewicht
- 88 kDa
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Gen-ID
- 25242
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NCBI Accession
- NM_012780, NP_036912
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UniProt
- P41739
Target
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