ADP-Ribosylation Factor GTPase Activating Protein 3 (ARFGAP3) (C-Term) Peptid
ARFGAP3
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN973372
Kurzübersicht für ADP-Ribosylation Factor GTPase Activating Protein 3 (ARFGAP3) (C-Term) Peptid (ABIN973372)
Target
ARFGAP3
(ADP-Ribosylation Factor GTPase Activating Protein 3 (ARFGAP3))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequenz
- SYWKKETSKD TETVLKTTGY SDRPTARRKP DYEPVENTDE AQKKFGNVKA
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-ARFGAP3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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ADP-Ribosylation Factor GTPase Activating Protein 3 (ARFGAP3) peptide
ARFGAP3 Reaktivität: Human, Maus, Rind (Kuh), Hund, Ratte Wirt: Synthetic BP, Imm
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- ARFGAP3 (ADP-Ribosylation Factor GTPase Activating Protein 3 (ARFGAP3))
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Hintergrund
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The protein encoded by this gene is a GTPase-activating protein (GAP) that associates with the Golgi apparatus and regulates the early secretory pathway of proteins. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1 (ARF1)-bound GTP, which is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is a prerequisite for the fusion of these vesicles with target compartments. The activity of this protein is sensitive to phospholipids. Multiple transcript variants encoding different isoforms have been found for this gene. This gene was originally known as ARFGAP1, but that is now the name of a related but different gene.
Alias Symbols: ARFGAP1, FLJ45618
Protein Interaction Partner: SMAD2
Protein Size: 516 -
Molekulargewicht
- 57 kDa
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Gen-ID
- 26286
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NCBI Accession
- NM_014570, NP_055385
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UniProt
- Q9NP61
Target
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