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ADP-Ribosylation Factor GTPase Activating Protein 1 (ARFGAP1) (Middle Region) Peptid

ARFGAP1 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN973371

Kurzübersicht für ADP-Ribosylation Factor GTPase Activating Protein 1 (ARFGAP1) (Middle Region) Peptid (ABIN973371)

Target

ARFGAP1 (ADP-Ribosylation Factor GTPase Activating Protein 1 (ARFGAP1))

Spezies

Human

Quelle

  • 5
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    Middle Region

    Sequenz

    WRDVTTFFSG KAEGPLDSPS EGHSYQNSGL DHFQNSNIDQ SFWETFGSAE

    Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti-ARFGAP1 Antibody(ARP57150_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Aufreinigung

    Purified
  • Applikationshinweise

    Each Investigator should determine their own optimal working dilution for specific applications.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Konzentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    ARFGAP1 (ADP-Ribosylation Factor GTPase Activating Protein 1 (ARFGAP1))

    Hintergrund

    The protein encoded by this gene is a GTPase-activating protein (GAP) which associates with the Golgi apparatus and which interacts with ADP-ribosylation factor 1 (ARF1). The encoded protein promotes hydrolysis of ARF1-bound GTP and is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is required for the fusion of these vesicles with target compartments. The activity of this protein is stimulated by phosphoinosides and inhibited by phosphatidylcholine. Two transcript variants encoding different isoforms have been found for this gene.

    Alias Symbols: ARF1GAP, HRIHFB2281, MGC39924

    Protein Interaction Partner: ARF1,COPA,CSNK1D,CYTH2,KDELR1,RGS2,TMED2,COPA,KDELR1,RGS2

    Protein Size: 406

    Molekulargewicht

    45 kDa

    Gen-ID

    55738

    NCBI Accession

    NM_018209, NP_060679

    UniProt

    Q8N6T3
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