This is a synthetic peptide designed for use in combination with anti-AP1B1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Each Investigator should determine their own optimal working dilution for specific applications.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Konzentration
1 mg/mL
Buffer
Final peptide concentration is 1 mg/mL in PBS.
Handhabung
Avoid repeated freeze-thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Target
AP1B1
(Adaptor-Related Protein Complex 1, beta 1 Subunit (AP1B1))
Hintergrund
This gene encodes the alpha 1 adaptin subunit of the adaptor protein 2 (AP-2) complex found in clathrin coated vesicles. The AP-2 complex is a heterotetramer consisting of two large adaptins (alpha or beta), a medium adaptin (mu), and a small adaptin (sigma). The complex is part of the protein coat on the cytoplasmic face of coated vesicles which links clathrin to receptors in vesicles. Alternative splicing of this gene results in two transcript variants encoding two different isoforms. A third transcript variant has been described, but its full length nature has not been determined.
Alias Symbols: ADTB1, AP105A, BAM22, CLAPB2
Protein Interaction Partner: AP2S1,BIN1,CLINT1,DEK,DNM2,EPN1,EPS15,GHR,HIP1,NAGPA,NUMB,PICALM,RAB11FIP2,RIT1,SHBG,SHC1,SMAD9,SNAP29,SYT3,SYT7,TOE1,CD22,CLINT1,DPYSL2,EHD1,EPS15,L1CAM,NAGPA,NUMB,PIN1,RAB11FIP2,UBC