PHAP1 (ANP32A)
(Acidic (Leucine-Rich) Nuclear phosphoprotein 32 Family, Member A (ANP32A))
Spezies
Human
Quelle
Synthetic
Applikation
Western Blotting (WB), Blocking Peptide (BP), Immunohistochemistry (IHC)
Produktmerkmale
This is a synthetic peptide designed for use in combination with anti-ANP32A antibody (Catalog #: ARP40203_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Each Investigator should determine their own optimal working dilution for specific applications.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Konzentration
1 mg/mL
Buffer
Final peptide concentration is 1 mg/mL in PBS.
Handhabung
Avoid repeated freeze-thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Target
PHAP1 (ANP32A)
(Acidic (Leucine-Rich) Nuclear phosphoprotein 32 Family, Member A (ANP32A))
Synonyme
C15orf1 Peptide, HPPCn Peptide, I1PP2A Peptide, LANP Peptide, MAPM Peptide, PHAP1 Peptide, PHAPI Peptide, PP32 Peptide, Anp32 Peptide, W91701 Peptide, pp32 Peptide, Anp32a Peptide, CG5784 Peptide, CT18148 Peptide, CT42180 Peptide, Dmel\\CG5784 Peptide, anon-EST:fe3A2 Peptide, wu:fj36e08 Peptide, zgc:55516 Peptide, ANP32D Peptide, acidic nuclear phosphoprotein 32 family member A Peptide, acidic (leucine-rich) nuclear phosphoprotein 32 family, member A Peptide, CG5784 gene product from transcript CG5784-RB Peptide, acidic nuclear phosphoprotein 32 family member A L homeolog Peptide, ANP32A Peptide, Anp32a Peptide, Mapmodulin Peptide, anp32a Peptide, anp32a.L Peptide
Hintergrund
ANP32A is a novel potent heat-stable inhibitor protein of protein phosphatase 2A. It may play a key role in self-renewing cell populations where it may act in the nucleus to limit their sensitivity to transformation. Being a tumor suppressor, ANP32A represses cell growth through inhibition of transcription by blocking acetylation and phosphorylation of histone H3 and initiating its proapoptotic activity.
Alias Symbols: LANP, MAPM, PP32, HPPCn, PHAP1, PHAPI, I1PP2A, C15orf1
Protein Interaction Partner: ESR1,RARA,THRB,ADAP1,APEX1,ATXN1,AXIN1,E4F1,ELAVL1,HSPB3,KPNA1,KPNA5,KPNA6,MAP1B,NSFL1C,PTPRC,SET,ADAP1,APEX1,ATXN1,AXIN1,HIST3H3,HIST4H4,HSPB3,MAP1B,MEPCE,SET,TAF1A