Aminolevulinate, delta-, Synthase 1 (ALAS1) Peptid
Kurzübersicht für Aminolevulinate, delta-, Synthase 1 (ALAS1) Peptid (ABIN973092)
Target
Spezies
Quelle
Applikation
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-ALAS1 antibody (Catalog #: ARP54346_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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: "Renal Function Decline With Small Interfering RNA Silencing Aminolevulinic Acid Synthase 1 (ALAS1)." in: Kidney international reports, Vol. 6, Issue 7, pp. 1904-1911, (2021) (PubMed).
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- ALAS1 (Aminolevulinate, delta-, Synthase 1 (ALAS1))
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Hintergrund
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Delta-aminolevulinate synthase (ALAS, EC 2.3.1.37) catalyzes the condensation of glycine with succinyl-CoA to form delta-aminolevulinic acid. This nuclear-encoded mitochondrial enzyme is the first and rate-limiting enzyme in the mammalian heme biosynthetic pathway. There are 2 tissue-specific isozymes: a housekeeping enzyme encoded by the ALAS1 gene and an erythroid tissue-specific enzyme encoded by ALAS2.
Alias Symbols: ALAS, ALAS3, ALASH, MIG4
Protein Interaction Partner: STAMBP
Protein Size: 640 -
Molekulargewicht
- 70 kDa
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Gen-ID
- 211
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NCBI Accession
- NM_000688, NP_000679
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UniProt
- P13196
Target
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