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Aminolevulinate, delta-, Synthase 1 (ALAS1) Peptid

Name: Aminolevulinate, delta-, Synthase 1 (ALAS1) Peptid
SKU: ABIN973092
Price: 150.78 EUR
Availability: InStock

ALAS1 Reaktivität: Human Wirt: Synthetic BP, WB

(1 reference)

Produktnummer ABIN973092

Kurzübersicht für Aminolevulinate, delta-, Synthase 1 (ALAS1) Peptid (ABIN973092)

ALAS1 (Aminolevulinate, delta-, Synthase 1 (ALAS1))

Human

Synthetic

Blocking Peptide (BP), Western Blotting (WB)

Produktmerkmale

This is a synthetic peptide designed for use in combination with anti-ALAS1 antibody (Catalog #: ARP54346_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

Aufreinigung

Purified
Aminolevulinate, delta-, Synthase 1 (ALAS1) peptide
ALAS1 Reaktivität: Säugetier Wirt: Synthetic BP, WB, IHC

Aminolevulinate, delta-, Synthase 1 (ALAS1) (N-Term) peptide
ALAS1 Reaktivität: Human Wirt: Synthetic BP, WB

Applikationshinweise

Each Investigator should determine their own optimal working dilution for specific applications.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Lyophilized

Rekonstitution

Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

Konzentration

1 mg/mL

Buffer

Final peptide concentration is 1 mg/mL in PBS.

Handhabung

Avoid repeated freeze-thaw cycles.

Lagerung

-20 °C

Informationen zur Lagerung

For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Lazareth, Poli, Bignon, Mirmiran, Rabant, Cohen, Schmitt, Puy, Karras, Gouya, Pallet: "Renal Function Decline With Small Interfering RNA Silencing Aminolevulinic Acid Synthase 1 (ALAS1)." in: Kidney international reports, Vol. 6, Issue 7, pp. 1904-1911, (2021) (PubMed).
Target

ALAS1 (Aminolevulinate, delta-, Synthase 1 (ALAS1))

Hintergrund

Delta-aminolevulinate synthase (ALAS, EC 2.3.1.37) catalyzes the condensation of glycine with succinyl-CoA to form delta-aminolevulinic acid. This nuclear-encoded mitochondrial enzyme is the first and rate-limiting enzyme in the mammalian heme biosynthetic pathway. There are 2 tissue-specific isozymes: a housekeeping enzyme encoded by the ALAS1 gene and an erythroid tissue-specific enzyme encoded by ALAS2.

Alias Symbols: ALAS, ALAS3, ALASH, MIG4

Protein Interaction Partner: STAMBP

Protein Size: 640

Molekulargewicht

70 kDa

Gen-ID

211

NCBI Accession

NM_000688, NP_000679

UniProt

P13196

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