Dihydrodiol Dehydrogenase (DDH) (N-Term) Peptid
DDH
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN973074
Kurzübersicht für Dihydrodiol Dehydrogenase (DDH) (N-Term) Peptid (ABIN973074)
Target
AKR1C1 (DDH)
(Dihydrodiol Dehydrogenase (DDH))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequenz
- DSAHLYNNEE QVGLAIRSKI ADGSVKREDI FYTSKLWCNS HRPELVRPAL
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-AKR1C1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- AKR1C1 (DDH) (Dihydrodiol Dehydrogenase (DDH))
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Hintergrund
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This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.
Alias Symbols: 2-ALPHA-HSD, 20-ALPHA-HSD, C9, DD1, DDH, DDH1, H-37, HAKRC, MBAB, MGC8954, HBAB, DD1/DD2
Protein Size: 323 -
Molekulargewicht
- 36 kDa
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Gen-ID
- 1645
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NCBI Accession
- NM_001353, NP_001344
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UniProt
- Q04828
Target
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