Acylglycerol Kinase (AGK) (N-Term) Peptid
AGK
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN972994
Kurzübersicht für Acylglycerol Kinase (AGK) (N-Term) Peptid (ABIN972994)
Target
Acylglycerol Kinase (AGK)
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequenz
- KKLLELMENT DVIIVAGGDG TLQEVVTGVL RRTDEATFSK IPIGFIPLGE
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-AGK Antibody(ARP57170_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Acylglycerol Kinase (AGK) peptide
AGK Reaktivität: Human, Maus Wirt: Synthetic BP, Imm
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Acylglycerol Kinase (AGK)
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Hintergrund
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AGK is a lipid kinase that can phosphorylate both monoacylglycerol and diacylglycerol to form lysophosphatidic acid (LPA) and phosphatidic acid (PA), respectively. AGK does not phosphorylate sphingosine. Overexpression of AGK increases the formation and secretion of LPA, resulting in transactivation of EGFR and activation of the downstream MAPK signaling pathway, leading to increased cell growth.
Alias Symbols: FLJ10842, MULK, MTDPS10
Protein Interaction Partner: HCK,PDLIM1,SNX4
Protein Size: 422 -
Molekulargewicht
- 47 kDa
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Gen-ID
- 55750
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NCBI Accession
- NM_018238, NP_060708
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UniProt
- Q53H12
Target
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