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Amino-terminal Enhancer of Split (AES) (Middle Region) Peptid

AES Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN972974

Kurzübersicht für Amino-terminal Enhancer of Split (AES) (Middle Region) Peptid (ABIN972974)

Target

AES (Amino-terminal Enhancer of Split (AES))

Spezies

Human

Quelle

  • 7
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    Middle Region

    Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti-AES antibody (Catalog #: ARP32323_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Aufreinigung

    Purified
  • Applikationshinweise

    Each Investigator should determine their own optimal working dilution for specific applications.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Konzentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    AES (Amino-terminal Enhancer of Split (AES))

    Hintergrund

    AES is similar in sequence to the amino terminus of Drosophila enhancer of split groucho, a protein involved in neurogenesis during embryonic development. The protein, which belongs to the groucho/TLE family of proteins, can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes.The protein encoded by this gene is similar in sequence to the amino terminus of Drosophila enhancer of split groucho, a protein involved in neurogenesis during embryonic development. The encoded protein, which belongs to the groucho/TLE family of proteins, can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes. Three transcript variants encoding different isoforms have been found for this gene.

    Alias Symbols: AES-1, AES-2, ESP1, GRG, GRG5, TLE5

    Protein Interaction Partner: AES,RELA,SIX1,SIX2,SIX3,SIX6,PTRH2,AR,ATN1,CCL7,GABARAP,GFI1B,GTF2E1,HMGB1,MED31,MSX1,POU2F1,PRDM1,PTRH2,RELA,RPL18A,SH3GL3,SIX1,SIX2,SIX3,SIX6,SNCAIP,AES,AR,GTF2E1,HMGB1,HNF1A,HNRNPAB,MED31,PTRH2,RELA,RUNX1,SH3GL3,SIX3,SIX6,STYXL1,TLE1,TLE3

    Protein Size: 264

    Molekulargewicht

    29 kDa

    Gen-ID

    166

    NCBI Accession

    NM_198969, NP_945320

    UniProt

    Q14CJ1
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