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Adducin 3 (Gamma) (ADD3) (C-Term) Peptid

ADD3 Reaktivität: Human Wirt: Synthetic BP, WB, ICC
Produktnummer ABIN972931
  • Target Alle ADD3 Produkte
    ADD3 (Adducin 3 (Gamma) (ADD3))
    Protein Region
    C-Term
    Spezies
    Human
    Quelle
    • 4
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB), Immunocytochemistry (ICC)
    Sequenz
    DELAKRVSRL STSTTIENIE ITIKSPEKIE EVLSPEGSPS KSPSKKKKKF
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-ADD3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    ADD3 (Adducin 3 (Gamma) (ADD3))
    Hintergrund
    Adducins are heteromeric proteins composed of different subunits referred to as adducin alpha, beta and gamma. The three subunits are encoded by distinct genes and belong to a family of membrane skeletal proteins involved in the assembly of spectrin-actin network in erythrocytes and at sites of cell-cell contact in epithelial tissues. Polymorphisms resulting in amino acid substitutions in these two subunits have been associated with the regulation of blood pressure in an animal model of hypertension. Heterodimers consisting of alpha and gamma subunits have also been described. Structurally, each subunit is comprised of two distinct domains.

    Alias Symbols: ADDL

    Protein Interaction Partner: PRKCA

    Protein Size: 706
    Molekulargewicht
    78 kDa
    Gen-ID
    120
    NCBI Accession
    NM_001121, NP_001112
    UniProt
    Q9UEY8
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