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Acyl-CoA Synthetase Long-Chain Family Member 4 (ACSL4) Peptid

ACSL4 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN972849

Kurzübersicht für Acyl-CoA Synthetase Long-Chain Family Member 4 (ACSL4) Peptid (ABIN972849)

Target

ACSL4 (Acyl-CoA Synthetase Long-Chain Family Member 4 (ACSL4))

Spezies

Human

Quelle

  • 3
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB)
  • Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti-ACSL4 antibody (Catalog #: ARP49774_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Aufreinigung

    Purified
  • Applikationshinweise

    Each Investigator should determine their own optimal working dilution for specific applications.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Konzentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    ACSL4 (Acyl-CoA Synthetase Long-Chain Family Member 4 (ACSL4))

    Hintergrund

    ACSL4 is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme preferentially utilizes arachidonate as substrate. The absence of this enzyme may contribute to the mental retardation or Alport syndrome. Alternative splicing of this gene generates 2 transcript variants.The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme preferentially utilizes arachidonate as substrate. The absence of this enzyme may contribute to the mental retardation or Alport syndrome. Alternative splicing of this gene generates 2 transcript variants.

    Alias Symbols: ACS4, FACL4, LACS4, MRX63, MRX68

    Protein Size: 670

    Molekulargewicht

    74 kDa

    Gen-ID

    2182

    NCBI Accession

    NM_004458, NP_004449

    UniProt

    O60488
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