Alkaline Ceramidase 1 (ACER1) (C-Term) Peptid
ACER1
Reaktivität: Human
Wirt: Synthetic
BP, WB
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- Target Alle ACER1 Produkte
- ACER1 (Alkaline Ceramidase 1 (ACER1))
- Protein Region
- C-Term
- Spezies
- Human
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Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Sequenz
- ITFPYGMVTM ALVDANYEMP GETLKVRYWP RDSWPVGLPY VEIRGDDKDC
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-ACER1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Aufreinigung
- Purified
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-
- Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Konzentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- ACER1 (Alkaline Ceramidase 1 (ACER1))
- Hintergrund
-
ACER1 hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid at an optimal pH of 8.0. It has a highly restricted substrate specificity for the natural stereoisomer of ceramide with D-erythro-sphingosine but not D-ribo-phytosphingosine or D-erythro-dihydrosphingosine as a backbone. It may have a role in regulating the levels of bioactive lipids ceramide and sphingosine 1-phosphate, as well as complex sphingolipids.
Alias Symbols: ASAH3, MGC138327, MGC138329, ALKCDase1
Protein Size: 264 - Molekulargewicht
- 31 kDa
- Gen-ID
- 125981
- NCBI Accession
- NM_133492, NP_597999
- UniProt
- Q8TDN7
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