Amiloride-Sensitive Cation Channel 3 (ACCN3) Peptid
ACCN3
Reaktivität: Human
Wirt: Synthetic
BP, WB, IHC
Produktnummer ABIN972802
Kurzübersicht für Amiloride-Sensitive Cation Channel 3 (ACCN3) Peptid (ABIN972802)
Target
ASIC3 (ACCN3)
(Amiloride-Sensitive Cation Channel 3 (ACCN3))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-ACCN3 antibody (Catalog #: ARP35152_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Amiloride-Sensitive Cation Channel 3 (ACCN3) peptide
ACCN3 Wirt: Synthetic BP, WB, IHC
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- ASIC3 (ACCN3) (Amiloride-Sensitive Cation Channel 3 (ACCN3))
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Hintergrund
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ACCN3 encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, two hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. ACCN3 encodes a member that is an acid sensor and may play an important role in the detection of lasting pH changes. In addition, a heteromeric association between this member and ACCN1 has been observed as proton-gated channels sensitive to gadolinium.
Alias Symbols: ACCN3, TNaC1, DRASIC, SLNAC1
Protein Interaction Partner: DLG4,GOPC,LIN7B,MAGI1,ACCN1,ACCN3,CSNK2A1,DLG4,GOPC,INADL,LIN7B,MAGI1,STOM,ACCN1,DLG4,GOPC,LIN7B,MAGI1,PRKACA,STOML1
Protein Size: 531 -
Molekulargewicht
- 58 kDa
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Gen-ID
- 9311
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NCBI Accession
- NM_004769, NP_004760
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UniProt
- Q9UHC3
Target
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