alpha-2-Macroglobulin (A2M) (N-Term) Peptid
A2M
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN972683
Kurzübersicht für alpha-2-Macroglobulin (A2M) (N-Term) Peptid (ABIN972683)
Target
alpha 2 Macroglobulin (A2M)
(alpha-2-Macroglobulin (A2M))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequenz
- PVPGHVTVSI CRKYSDASDC HGEDSQAFCE KFSGQLNSHG CFYQQVKTKV
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-A2M Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- alpha 2 Macroglobulin (A2M) (alpha-2-Macroglobulin (A2M))
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Hintergrund
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Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits.
Alias Symbols: CPAMD5, DKFZp779B086, FWP007, S863-7, A2MD
Protein Interaction Partner: ADAM19,ADAMTS1,AMBP,ANXA6,APOE,ATF7IP,B2M,C11orf58,CELA1,CTSB,CTSE,HSPA5,IL10,IL1B,KLK2,KLK3,LCAT,LEP,LRP1,LYZ,MMP2,MYOC,NGF,PAEP,PDGFA,PDGFB,SHBG,TGFBI,STAT3,ADAMTS1,AMBP,ANXA7,APOE,B2M,C11orf58,CDC42,CDK2AP2,CDKN1A,CPB2,GEM,GRB2,H2AFX,HMOX2,HSPA5,IL10,IL4,KLK13,KLK3,LCAT,LEP,LRP1,MMP2,NGF,NUDT21,PAEP,RAP1B,RPP14,SEPT8,SMN1,TGIF1,TK1,TNFRSF14,TSC22D1,TTR,UFD1L
Protein Size: 1474 -
Molekulargewicht
- 161 kDa
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Gen-ID
- 2
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NCBI Accession
- NM_000014, NP_000005
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UniProt
- P01023
Target
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