A synthetic peptide for use as a blocking control in assays to test for specificity of HTRA4 antibody, Alternative Names: HTRA4 control peptide, HTRA4 antibody Blocking Peptide, Anti-HTRA4 Blocking Peptide, Htra Serine Peptidase 4 Blocking Peptide, FLJ90724 Blocking Peptide
Optimal conditions should be determined by the investigator
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Handhabung
Avoid repeated freeze/thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20 °C long term.
Target
HTRA4
(HtrA Serine Peptidase 4 (HTRA4))
Hintergrund
HTRA4 is a member of the HtrA family of proteases. The protein contains a putative signal peptide, an insulin growth factor binding domain, a Kazal protease inhibitor domain, a conserved trypsin domain and a PDZ domain. Based on studies on other related family members, this enzyme may function as a secreted oligomeric chaperone protease to degrade misfolded secretory proteins. Other human HtrA proteins have been implicated in arthritis, tumor suppression, unfolded stress response, apoptosis, and aging.