A synthetic peptide for use as a blocking control in assays to test for specificity of TPM1 antibody, Alternative Names: Tropomyosin 1 control peptide, Tropomyosin 1 antibody Blocking Peptide, Anti-Tropomyosin 1 Blocking Peptide, TPM1 Blocking Peptide, C15orf13 Blocking Peptide, HTM-alpha Blocking Peptide, TMSA Blocking Peptide, Tropomyosin 1, Tropomyosin -1, Tropomyosin 1, Tropomyosin -1 Blocking Peptide, Tropomyosin 1 Blocking Peptide
Optimal conditions should be determined by the investigator
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Handhabung
Avoid repeated freeze/thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20 °C long term.
Target
Tropomyosin (TPM1)
(Tropomyosin 1 (Alpha) (TPM1))
Hintergrund
TPM1 is a member of the tropomyosin family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosin is composed of two alpha-helical chains arranged as a coiled-coil. It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments. The protein is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle, where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction.