Actinin, alpha 4 (ACTN4) Peptid
ACTN4
Reaktivität: Säugetier
Wirt: Synthetic
BP, WB, IHC
Produktnummer ABIN940431
Kurzübersicht für Actinin, alpha 4 (ACTN4) Peptid (ABIN940431)
Target
alpha Actinin 4 (ACTN4)
(Actinin, alpha 4 (ACTN4))
Spezies
Säugetier
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Protein-Typ
- Synthetic
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Sequenz
- LIHRHRPELI EYDKLRKDDP VTNLNNAFEV AEKYLDIPKM LDAEDIVNTA
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Produktmerkmale
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A synthetic peptide for use as a blocking control in assays to test for specificity of ACTN4 antibody,
Alternative Names: alpha Actinin 4 control peptide, alpha Actinin 4 antibody Blocking Peptide, Anti-alpha Actinin 4 Blocking Peptide, ACTN4 Blocking Peptide, DKFZp686K23158 Blocking Peptide, FSGS Blocking Peptide, FSGS1 Blocking Peptide
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Applikationshinweise
- Optimal conditions should be determined by the investigator
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handhabung
- Avoid repeated freeze/thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20 °C long term.
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- alpha Actinin 4 (ACTN4) (Actinin, alpha 4 (ACTN4))
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Hintergrund
- Alpha actinins belong to the spectrin superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. ACTN4 is a nonmuscle, alpha actinin isoform which is concentrated in the cytoplasm, and thought to be involved in metastatic processes. Alpha actinin is an actin-binding protein with multiple roles in different cell types.
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Molekulargewicht
- 100 kDa
Target
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