A synthetic peptide for use as a blocking control in assays to test for specificity of RNF128 antibody, Alternative Names: RNF128 control peptide, RNF128 antibody Blocking Peptide, Anti-RNF128 Blocking Peptide, Ring Finger Protein 128 Blocking Peptide, FLJ23516 Blocking Peptide, GRAIL Blocking Peptide, RNF128, RNF-128, RNF 128, RNF-128 Blocking Peptide, RNF 128 Blocking Peptide
Optimal conditions should be determined by the investigator
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Handhabung
Avoid repeated freeze/thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20 °C long term.
Target
RNF128
(Ring Finger Protein 128 (RNF128))
Hintergrund
RNF128 is a type I transmembrane protein that localizes to the endocytic pathway. This protein contains a RING zinc-finger motif and has been shown to possess E3 ubiquitin ligase activity. Expression of RNF128 in retrovirally transduced T cell hybridoma significantly inhibits activation-induced IL2 and IL4 cytokine production. Induced expression of RNF128 was observed in anergic CD4(+) T cells, which suggested a role in the induction of anergic phenotype.