A synthetic peptide for use as a blocking control in assays to test for specificity of IKZF3 antibody, Alternative Names: IKZF3 control peptide, IKZF3 antibody Blocking Peptide, Anti-IKZF3 Blocking Peptide, IKAROS family zinc finger 3, Aiolos Blocking Peptide, AIOLOS Blocking Peptide, ZNFN1A3 Blocking Peptide, IKZF3, IKZF-3, IKZF 3, IKZF-3 Blocking Peptide, IKZF 3 Blocking Peptide
IKZF3
Reaktivität: Human
Wirt: Synthetic
BP, WB, IHC
Applikationshinweise
Optimal conditions should be determined by the investigator
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Handhabung
Avoid repeated freeze/thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20 °C long term.
Target
IKZF3
(IKAROS Family Zinc Finger 3 (Aiolos) (IKZF3))
Hintergrund
IKZF3 is a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoetic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. At least six alternative transcripts encoding different isoforms have been described.