Suppressor of Cytokine Signaling 7 (SOCS7) Peptid
SOCS7
Reaktivität: Säugetier
Wirt: Synthetic
BP, WB, IHC
Produktnummer ABIN940239
Kurzübersicht für Suppressor of Cytokine Signaling 7 (SOCS7) Peptid (ABIN940239)
Target
SOCS7
(Suppressor of Cytokine Signaling 7 (SOCS7))
Spezies
Säugetier
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Protein-Typ
- Synthetic
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Sequenz
- LDPKALPPGL ALERTWGPAA GLEAQLAALG LGQPAGPGVK TVGGGCCPCP
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Produktmerkmale
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A synthetic peptide for use as a blocking control in assays to test for specificity of SOCS7 antibody,
Alternative Names: SOCS7 control peptide, SOCS7 antibody Blocking Peptide, Anti-SOCS7 Blocking Peptide, Suppressor Of Cytokine Signaling 7 Blocking Peptide, NAP4 Blocking Peptide, SOCS7, SOCS-7, SOCS 7, SOCS-7 Blocking Peptide, SOCS 7 Blocking Peptide
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Applikationshinweise
- Optimal conditions should be determined by the investigator
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handhabung
- Avoid repeated freeze/thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20 °C long term.
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- SOCS7 (Suppressor of Cytokine Signaling 7 (SOCS7))
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Hintergrund
- SOCS7 regulates signaling cascades probably through protein ubiquitination and/or sequestration. SOCS7 functions in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation. SOCS7 inhibits also prolactin, growth hormone and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in the cytoplasm and reducing their binding to DNA. SOCS7 may be a substrate recognition component of a SCF-like E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
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Molekulargewicht
- 64 kDa
Target
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