A synthetic peptide for use as a blocking control in assays to test for specificity of XRCC3 antibody, Alternative Names: XRCC3 control peptide, XRCC3 antibody Blocking Peptide, Anti-XRCC3 Blocking Peptide, X-ray repair complementing defective repair in Chinese hamster cells 3 Blocking Peptide, XRCC3, XRCC-3, XRCC 3, XRCC-3 Blocking Peptide, XRCC 3 Blocking Peptide
Optimal conditions should be determined by the investigator
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Handhabung
Avoid repeated freeze/thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20 °C long term.
Target
XRCC3
(X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 3 (XRCC3))
Hintergrund
This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complements Chinese hamster irs1SF, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents and is chromosomally unstable. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.