Crystallin, alpha B (CRYAB) Peptid
CRYAB
Reaktivität: Säugetier
Wirt: Synthetic
BP, WB, IHC
Produktnummer ABIN940136
Kurzübersicht für Crystallin, alpha B (CRYAB) Peptid (ABIN940136)
Target
CRYAB
(Crystallin, alpha B (CRYAB))
Spezies
Säugetier
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Protein-Typ
- Synthetic
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Sequenz
- KYRIPADVDP LTITSSLSSD GVLTVNGPRK QVSGPERTIP ITREEKPAVT
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Produktmerkmale
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A synthetic peptide for use as a blocking control in assays to test for specificity of CRYAB antibody,
Alternative Names: Crystallin Alpha B control peptide, Crystallin Alpha B antibody Blocking Peptide, Anti-Crystallin Alpha B Blocking Peptide, CRYAB Blocking Peptide, CRYA2 Blocking Peptide, CTPP2 Blocking Peptide, HSPB5 Blocking Peptide
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Crystallin, alpha B (CRYAB) peptide
CRYAB Reaktivität: Human, Maus, Ratte Wirt: Synthetic BP, Imm
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Applikationshinweise
- Optimal conditions should be determined by the investigator
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handhabung
- Avoid repeated freeze/thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20 °C long term.
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- CRYAB (Crystallin, alpha B (CRYAB))
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Hintergrund
- Alpha crystallins are composed of: alpha-A and alpha-B, for acidic and basic, respectively. They act as molecular chaperones although they do not renature proteins and release them in the fashion of a true chaperone, instead they hold them in large soluble aggregates. Post-translational modifications decrease the ability to chaperone. Two additional functions of alpha crystallins are an autokinase activity and participation in the intracellular architecture. Alpha-A and alpha-B are differentially expressed, alpha-A is preferentially restricted to the lens and alpha-B is expressed widely in many tissues and organs. Elevated expression of alpha-B crystallin occurs in many neurological diseases, a missense mutation cosegregated in a family with a desmin-related myopathy.
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Molekulargewicht
- 12 kDa
Target
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