Apolipoprotein E (APOE) Peptid
APOE
Reaktivität: Säugetier
Wirt: Synthetic
BP, IHC, WB
Produktnummer ABIN940102
Kurzübersicht für Apolipoprotein E (APOE) Peptid (ABIN940102)
Target
APOE
(Apolipoprotein E (APOE))
Spezies
Säugetier
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
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Protein-Typ
- Synthetic
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Sequenz
- KVLWAALLVT FLAGCQAKVE QAVETEPEPE LRQQTEWQSG QRWELALGRF
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Produktmerkmale
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A synthetic peptide for use as a blocking control in assays to test for specificity of APOE antibody,
Alternative Names: ApoE control peptide, ApoE antibody Blocking Peptide, Anti-ApoE Blocking Peptide, Apolipoprotein E Blocking Peptide, AD2 Blocking Peptide, MGC1571 Blocking Peptide, apoprotein Blocking Peptide
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Apolipoprotein E (APOE) peptide
APOE Reaktivität: Human Wirt: Synthetic BP, Imm
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Applikationshinweise
- Optimal conditions should be determined by the investigator
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handhabung
- Avoid repeated freeze/thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20 °C long term.
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- APOE (Apolipoprotein E (APOE))
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Hintergrund
- Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants.
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Molekulargewicht
- 34 kDa
Target
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