A synthetic peptide for use as a blocking control in assays to test for specificity of PARP16 antibody, Alternative Names: PARP16 control peptide, PARP16 antibody Blocking Peptide, Anti-PARP16 Blocking Peptide, Poly ADP-ribose polymerase family member 16 Blocking Peptide, Adp-Ribose Polymerase 16 Blocking Peptide, PARP16, PARP-16, PARP 16, PARP-16 Blocking Peptide, PARP 16 Blocking Peptide
Optimal conditions should be determined by the investigator
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Handhabung
Avoid repeated freeze/thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20 °C long term.
Target
PARP16
(Poly (ADP-Ribose) Polymerase Family, Member 16 (PARP16))
Hintergrund
Poly(ADP-ribosyl)ation is an immediate DNA-damage-dependent post-translational modification of histones and other nuclear proteins that contributes to the survival of injured proliferating cells. PARP16 is a member of poly(ADP-ribose) polymerases (PARPs) family that is encoded by different genes and displaying a conserved catalytic domain in which PARP-1 (113 kDa), the founding member, and PARP-2 (62 kDa) are so far the sole enzymes whose catalytic activity has been shown to be immediately stimulated by DNA strand breaks.