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E3 ubiquitin-protein ligase RAD18 (RAD18) Peptid

RAD18 Reaktivität: Säugetier Wirt: Synthetic BP, WB, IHC
Produktnummer ABIN940003
382,12 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μg
Lieferung nach: Deutschland
Lieferung in 20 bis 27 Werktagen

Kurzübersicht für E3 ubiquitin-protein ligase RAD18 (RAD18) Peptid (ABIN940003)

Target

RAD18 (E3 ubiquitin-protein ligase RAD18 (RAD18))

Spezies

Säugetier

Quelle

  • 4
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
  • Protein-Typ

    Synthetic

    Sequenz

    KQVTKVDCPV CGVNIPESHI NKHLDSCLSR EEKKESLRSS VHKRKPLPKT

    Produktmerkmale

    A synthetic peptide for use as a blocking control in assays to test for specificity of RAD18 antibody,
    Alternative Names: RAD18 control peptide, RAD18 antibody Blocking Peptide, Anti-RAD18 Blocking Peptide, Rad18 Homolog Blocking Peptide, RNF73 Blocking Peptide, RAD18, RAD-18, RAD 18, RAD-18 Blocking Peptide, RAD 18 Blocking Peptide
  • Applikationshinweise

    Optimal conditions should be determined by the investigator

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.

    Buffer

    PBS

    Handhabung

    Avoid repeated freeze/thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20 °C long term.
  • Target

    RAD18 (E3 ubiquitin-protein ligase RAD18 (RAD18))

    Hintergrund

    RAD18 is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Similar to its yeast counterpart, RAD18 is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif. Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens.

    Molekulargewicht

    56 kDa
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