A synthetic peptide for use as a blocking control in assays to test for specificity of C1 orf166 antibody, Alternative Names: C1ORF166 control peptide, C1ORF166 antibody Blocking Peptide, Anti-C1ORF166 Blocking Peptide, FLJ12875 Blocking Peptide, RP.2 Blocking Peptide
Optimal conditions should be determined by the investigator
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Handhabung
Avoid repeated freeze/thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20 °C long term.
Target
MUL1
(Mitochondrial E3 Ubiquitin Protein Ligase 1 (MUL1))
Hintergrund
C1orf166 encodes an ubiquitin-protein ligase that plays a role in the control of mitochondrial morphology. Promotes mitochondrial fragmentation and influences mitochondrial localization. Inhibits cell growth. When overexpressed, activates JNK through MAP3K7/TAK1 and induces caspase-dependent apoptosis. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.