A synthetic peptide for use as a blocking control in assays to test for specificity of GLP2 R antibody, Alternative Names: GLP2R control peptide, GLP2R antibody Blocking Peptide, Anti-GLP2R Blocking Peptide, Glucagon-Like Peptide 2 Receptor Blocking Peptide, GLP-2R Blocking Peptide, GLP2, GLP-2, GLP 2, GLP-2 Blocking Peptide, GLP 2 Blocking Peptide
The GLP2 receptor (GLP2R) is a G protein-coupled receptor superfamily member closely related to the glucagon receptor ans GLP1 receptor. Glucagon-like peptide-2 (GLP2) is a 33-amino acid proglucagon-derived peptide produced by intestinal enteroendocrine cells. Like glucagon-like peptide-1 (GLP1) and glucagon itself, it is derived from the proglucagon peptide encoded by the GCG gene. GLP2 stimulates intestinal growth and upregulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. Moreover, GLP2 prevents intestinal hypoplasia resulting from total parenteral nutrition.