A synthetic peptide for use as a blocking control in assays to test for specificity of GLP2 R antibody, Alternative Names: GLP2R control peptide, GLP2R antibody Blocking Peptide, Anti-GLP2R Blocking Peptide, Glucagon-Like Peptide 2 Receptor Blocking Peptide, GLP-2R Blocking Peptide, GLP2, GLP-2, GLP 2, GLP-2 Blocking Peptide, GLP 2 Blocking Peptide
Optimal conditions should be determined by the investigator
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Handhabung
Avoid repeated freeze/thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20 °C long term.
Target
GLP2R
(Glucagon-Like Peptide 2 Receptor (GLP2R))
Hintergrund
The GLP2 receptor (GLP2R) is a G protein-coupled receptor superfamily member closely related to the glucagon receptor ans GLP1 receptor. Glucagon-like peptide-2 (GLP2) is a 33-amino acid proglucagon-derived peptide produced by intestinal enteroendocrine cells. Like glucagon-like peptide-1 (GLP1) and glucagon itself, it is derived from the proglucagon peptide encoded by the GCG gene. GLP2 stimulates intestinal growth and upregulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. Moreover, GLP2 prevents intestinal hypoplasia resulting from total parenteral nutrition.