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Aldolase B, Fructose-Bisphosphate (ALDOB) Peptid

ALDOB Reaktivität: Säugetier Wirt: Synthetic BP, WB, IHC
Produktnummer ABIN939889
  • Target Alle ALDOB Produkte
    ALDOB (Aldolase B, Fructose-Bisphosphate (ALDOB))
    Protein-Typ
    Synthetic
    Spezies
    Säugetier
    Quelle
    • 3
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    KLDQGGAPLA GTNKETTIQG LDGLSERCAQ YKKDGVDFGK WRAVLRIADQ
    Produktmerkmale
    A synthetic peptide for use as a blocking control in assays to test for specificity of ALDOB antibody,
    Alternative Names: ALDOB control peptide, ALDOB antibody Blocking Peptide, Anti-ALDOB Blocking Peptide, Aldolase B Fructose-Bisphosphate Blocking Peptide, ALDB Blocking Peptide
  • Applikationshinweise
    Optimal conditions should be determined by the investigator
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
    Buffer
    PBS
    Handhabung
    Avoid repeated freeze/thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C long term.
  • Target
    ALDOB (Aldolase B, Fructose-Bisphosphate (ALDOB))
    Hintergrund
    Fructose-1,6-bisphosphate aldolase (EC 4.1.2.13) is a tetrameric glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Vertebrates have 3 aldolase isozymes which are distinguished by their electrophoretic and catalytic properties. Differences indicate that aldolases A, B, and C are distinct proteins, the products of a family of related 'housekeeping' genes exhibiting developmentally regulated expression of the different isozymes. The developing embryo produces aldolase A, which is produced in even greater amounts in adult muscle where it can be as much as 5 % of total cellular protein. In adult liver, kidney and intestine, aldolase A expression is repressed and aldolase B is produced. In brain and other nervous tissue, aldolase A and C are expressed about equally. There is a high degree of homology between aldolase A and C. Defects in ALDOB cause hereditary fructose intolerance.
    Molekulargewicht
    39 kDa
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