A synthetic peptide for use as a blocking control in assays to test for specificity of DSG2 antibody, Alternative Names: Desmoglein 2 control peptide, Desmoglein 2 antibody Blocking Peptide, Anti-Desmoglein 2 Blocking Peptide, ARVC10 Blocking Peptide, ARVD10 Blocking Peptide, CDHF5 Blocking Peptide, HDGC Blocking Peptide, MGC117034 Blocking Peptide, MGC117036 Blocking Peptide, MGC117037 Blocking Peptide, DSG2 Blocking Peptide
Optimal conditions should be determined by the investigator
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Handhabung
Avoid repeated freeze/thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20 °C long term.
Target
Desmoglein 2 (DSG2)
Hintergrund
Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. DSG2 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This second family member is expressed in colon, colon carcinoma, and other simple and stratified epithelial-derived cell lines.