E3 SUMO-Protein Ligase NSE2 (NSMCE2) Peptid
NSMCE2
Reaktivität: Säugetier
Wirt: Synthetic
BP, WB, IHC
-
- Target Alle NSMCE2 Produkte
- NSMCE2 (E3 SUMO-Protein Ligase NSE2 (NSMCE2))
- Protein-Typ
- Synthetic
- Spezies
- Säugetier
-
Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Sequenz
- KFLALQSKNS DADFQNNEKF VQFKQQLKEL KKQCGLQADR EADGTEGVDE
- Produktmerkmale
-
A synthetic peptide for use as a blocking control in assays to test for specificity of NSMCE2 antibody,
Alternative Names: NSMCE2 control peptide, NSMCE2 antibody Blocking Peptide, Anti-NSMCE2 Blocking Peptide, Non-Smc Element 2 Mms21 Homolog Blocking Peptide, C8orf36 Blocking Peptide, FLJ32440 Blocking Peptide, MMS21 Blocking Peptide, NSE2 Blocking Peptide, NSMCE2, NSMCE-2, NSMCE 2, NSMCE-2 Blocking Peptide, NSMCE 2 Blocking Peptide - Aufreinigung
- Immunoaffinity chromatography
-
-
- Applikationshinweise
- Optimal conditions should be determined by the investigator
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Lyophilized
- Rekonstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
- Buffer
- PBS
- Handhabung
- Avoid repeated freeze/thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C long term.
-
- Target
- NSMCE2 (E3 SUMO-Protein Ligase NSE2 (NSMCE2))
- Synonyme
- 1110014D18Rik Peptide, AI661537 Peptide, RGD1305156 Peptide, C8orf36 Peptide, MMS21 Peptide, NSE2 Peptide, ZMIZ7 Peptide, Non-SMC element 2 Peptide, NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase Peptide, NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase L homeolog Peptide, Smc5-6 complex non-SMC subunit 2 Peptide, Nsmce2 Peptide, NSMCE2 Peptide, nsmce2.L Peptide, nse2 Peptide
- Hintergrund
- NSMCE2 is the E3 SUMO-protein ligase component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. NSMCE2 acts as a E3 ligase mediating SUMO attachment to various proteins such as SMC6L1 and TRAX, and maybe the cohesin components RAD21 and STAG2. SUMO protein-ligase activity is required for the prevention of DNA damage-induced apoptosis by facilitating DNA repair.
- Molekulargewicht
- 28 kDa
-
Sie sind hier:
