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Bone Morphogenetic Protein 10 (BMP10) Peptid

BMP10 Reaktivität: Säugetier Wirt: Synthetic BP, WB, IHC
Produktnummer ABIN939752
382,12 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μg
Lieferung nach: Deutschland
Lieferung in 20 bis 27 Werktagen

Kurzübersicht für Bone Morphogenetic Protein 10 (BMP10) Peptid (ABIN939752)

Target

BMP10 (Bone Morphogenetic Protein 10 (BMP10))

Spezies

Säugetier

Quelle

  • 4
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
  • Protein-Typ

    Synthetic

    Sequenz

    KFATDRTSMP SANIIRSFKN EDLFSQPVSF NGIRKYPLLF NVSIPHHEEV

    Produktmerkmale

    A synthetic peptide for use as a blocking control in assays to test for specificity of Bmp10 antibody,
    Alternative Names: Bmp10 control peptide, Bmp10 antibody Blocking Peptide, Anti-Bmp10 Blocking Peptide, bone morphogenetic protein 10 Blocking Peptide, Bmp10 Blocking Peptide, Bmp10, Bmp-10, Bmp 10, Bmp-10 Blocking Peptide, Bmp 10 Blocking Peptide
  • Applikationshinweise

    Optimal conditions should be determined by the investigator

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.

    Buffer

    PBS

    Handhabung

    Avoid repeated freeze/thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20 °C long term.
  • Target

    BMP10 (Bone Morphogenetic Protein 10 (BMP10))

    Hintergrund

    Bmp10 is required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Bmp10 acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Bmp10 inhibits endothelial cell migration and growth.

    Molekulargewicht

    48 kDa
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