Mitogen-Activated Protein Kinase-Activated Protein Kinase 3 (MAPKAPK3) Peptid
MAPKAPK3
Reaktivität: Säugetier
Wirt: Synthetic
BP, WB, IHC
Produktnummer ABIN939713
Kurzübersicht für Mitogen-Activated Protein Kinase-Activated Protein Kinase 3 (MAPKAPK3) Peptid (ABIN939713)
Target
MAPKAP Kinase 3 (MAPKAPK3)
(Mitogen-Activated Protein Kinase-Activated Protein Kinase 3 (MAPKAPK3))
Spezies
Säugetier
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Protein-Typ
- Synthetic
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Sequenz
- KEEMTSALAT MRVDYDQVKI KDLKTSNNRL LNKRRKKQAG SSSASQGCNN
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Produktmerkmale
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A synthetic peptide for use as a blocking control in assays to test for specificity of MAPKAPK3 antibody,
Alternative Names: MAPKAPK3 control peptide, MAPKAPK3 antibody Blocking Peptide, Anti-MAPKAPK3 Blocking Peptide, mitogen-activated protein kinase-activated protein kinase 3 Blocking Peptide, 3PK Blocking Peptide, MAPKAP3 Blocking Peptide, MAPKAPK3, MAPKAPK-3, MAPKAPK 3, MAPKAPK-3 Blocking Peptide, MAPKAPK 3 Blocking Peptide
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Applikationshinweise
- Optimal conditions should be determined by the investigator
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handhabung
- Avoid repeated freeze/thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20 °C long term.
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- MAPKAP Kinase 3 (MAPKAPK3) (Mitogen-Activated Protein Kinase-Activated Protein Kinase 3 (MAPKAPK3))
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Hintergrund
- MAPKAPK3 is a member of the Ser/Thr protein kinase family. This kinase functions as a mitogen-activated protein kinase (MAP kinase)- activated protein kinase. MAP kinases are also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This kinase was shown to be activated by growth inducers and stress stimulation of cells. In vitro studies demonstrated that ERK, p38 MAP kinase and Jun N-terminal kinase were all able to phosphorylate and activate this kinase, which suggested the role of this kinase as an integrative element of signaling in both mitogen and stress responses. This kinase was reported to interact with, phosphorylate and repress the activity of E47, which is a basic helix-loop-helix transcription factor known to be involved in the regulation of tissue-specific gene expression and cell differentiation.
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Molekulargewicht
- 43 kDa
Target
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